Meghdad Rahdar

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index

Wen Shen, Cheryl Li De Hoyos, Michael T. Migawa et al. · Nature Biotechnology · 2019 · 333 citations

Medicine, Biochemistry, Pharmacology +13

A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN

Meghdad Rahdar, Takanari Inoue, Tobias Meyer et al. · Proceedings of the National Academy of Sciences · 2008 · 263 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Synthetic CRISPR RNA-Cas9–guided genome editing in human cells

Meghdad Rahdar, Moira A. McMahon, Thazha P. Prakash et al. · Proceedings of the National Academy of Sciences · 2015 · 180 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

A secretory kinase complex regulates extracellular protein phosphorylation

Jixin Cui, Junyu Xiao, Vincent S. Tagliabracci et al. · eLife · 2015 · 126 citations · Full text

Dentistry, Biochemistry, Molecular Biology +17

Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis

Jianzhong Wen, Junyu Xiao, Meghdad Rahdar et al. · Proceedings of the National Academy of Sciences · 2014 · 108 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16