Concepedia

K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology

Kotaro Sakamoto, Yusuke Kamada, Tomoya Sameshima, Masahiro Yaguchi, Ayumu Niida, Shigekazu Sasaki, Masanori Miwa, Shoichi Ohkubo, Junichi Sakamoto, Masahiro Kamaura,

Biochemical and Biophysical Research Communications · 2017 · 114 citations · 16 references

DOI

Concepts

References

16

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

J.M. Ostrem, Ulf Peters, Martin L. Sos et al. · Nature · 2013 · 2.5K citations · Full text

, , +14

An orthosteric inhibitor of the Ras-Sos interaction

Anupam Patgiri, Kamlesh Yadav, Paramjit S. Arora et al. · Nature Chemical Biology · 2011 · 294 citations

, , +14

The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B

Shaoyong Lu, Hyunbum Jang, Ruth Nussinov et al. · Scientific Reports · 2016 · 218 citations · Full text

, , +17

Inhibition of Ras Signaling by Blocking Ras–Effector Interactions with Cyclic Peptides

Punit Upadhyaya, Ziqing Qian, Nicholas G. Selner et al. · Angewandte Chemie International Edition · 2015 · 148 citations · Full text

, , +17

Cancer: The Ras renaissance

Heidi Ledford · Nature · 2015 · 131 citations · Full text

, , +11