Concepedia

Kotaro Sakamoto

KS

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Publications

40

Citations

1.4K

H-Index

22

Active since

1983

Affiliations

Takeda (Japan)(Current)

Kindai University

Ichimaru Pharcos (Japan)

Japanese Red Cross Society Wakayama Medical Center

The University of Osaka

Kotaro Sakamoto is an author at Takeda (Japan) specializing in medicine, pharmacology, and drug discovery.

ORCID

Top concepts

Publications per year

1983–2023

40

Publications

40

K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology

Kotaro Sakamoto, Yusuke Kamada, Tomoya Sameshima et al. · Biochemical and Biophysical Research Communications · 2017 · 110 citations

, , +9

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines

Masanobu Tsubaki, Makiko Komai, Shinichiro Fujimoto et al. · Journal of Experimental & Clinical Cancer Research · 2013 · 107 citations · Full text

Generation of KS-58 as the first K-Ras(G12D)-inhibitory peptide presenting anti-cancer activity in vivo

Kotaro Sakamoto, Teruaki Masutani, Takatsugu Hirokawa · Scientific Reports · 2020 · 82 citations · Full text

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

Satoshi Sogabe, Yusuke Kamada, Masanori Miwa et al. · ACS Medicinal Chemistry Letters · 2017 · 79 citations · Full text

, , +18

Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation

Masanobu Tsubaki, Makiko Komai, Tatsuki Itoh et al. · Journal of Biomedical Science · 2014 · 67 citations · Full text

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