Makiko Komai

Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines

Masanobu Tsubaki, Makiko Komai, Shinichiro Fujimoto et al. · Journal of Experimental & Clinical Cancer Research · 2013 · 108 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2

Masanobu Tsubaki, Takao Satou, Tatsuki Itoh et al. · Molecular and Cellular Endocrinology · 2012 · 77 citations

Life Sciences, Cell Biology, Pharmacology +17

Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma cells

Masanobu Tsubaki, Takao Satou, Tatsuki Itoh et al. · Leukemia Research · 2012 · 70 citations

Medicine, Cancer Biology, Oncology +12

Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation

Masanobu Tsubaki, Makiko Komai, Tatsuki Itoh et al. · Journal of Biomedical Science · 2014 · 70 citations · Full text

Medicine, Cell Biology, Pharmacology +15

By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells

Masanobu Tsubaki, Makiko Komai, Tatsuki Itoh et al. · Leukemia Research · 2013 · 51 citations

Medicine, Oncology, Pharmacology +12