Metastin and its variant forms suppress migration of pancreatic cancer cells

Toshihiko Masui, Ryuichiro Doi, Tomohiko Mori, +10

Biochemical and Biophysical Research Communications

Tumor BiologyPancreatic CancerMedicinePathologyPancreatic Cancer Cells +3

Unequivocal Synthesis of (<i>Z</i>)-Alkene and (<i>E</i>)-Fluoroalkene Dipeptide Isosteres To Probe Structural Requirements of the Peptide Transporter PEPT1

Ayumu Niida, Kenji Tomita, Makiko Mizumoto, +6

Organic Letters

Peptide Transporter Pept1Molecular BiologyOrganic ChemistryPeptide SciencePeptide Therapeutics +15

K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology

Kotaro Sakamoto, Yusuke Kamada, Tomoya Sameshima, +9

Biochemical and Biophysical Research Communications

BiochemistryMedicineNatural SciencesPeptide EngineeringPeptide Library +7

Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d

Satoshi Sogabe, Yusuke Kamada, Masanori Miwa, +7

ACS Medicinal Chemistry Letters

Crystal StructureProtein AssemblyMolecular BiologyCell DifferentiationCancer Biology +16

Design and synthesis of downsized metastin (45–54) analogs with maintenance of high GPR54 agonistic activity

Ayumu Niida, Zixuan Wang, Kenji Tomita, +7

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyPharmaceutical ScienceMedicineDrug DevelopmentPharmacology +3

Transport Characteristics of a Novel Peptide Transporter 1 Substrate, Antihypotensive Drug Midodrine, and Its Amino Acid Derivatives

Masahiro Tsuda, Tomohiro Terada, Megumi Irie, +5

Journal of Pharmacology and Experimental Therapeutics

Diastereoselective Synthesis of New <i>ψ</i>[(<i>E</i>)-CHCMe]- and <i>ψ</i>[(<i>Z</i>)-CHCMe]-type Alkene Dipeptide Isosteres by Organocopper Reagents and Application to Conformationally Restricted Cyclic RGD Peptidomimetics

Shinya Oishi, Takae Kamano, Ayumu Niida, +6

The Journal of Organic Chemistry

Structure–activity relationship study on small peptidic GPR54 agonists

Kenji Tomita, Ayumu Niida, Shinya Oishi, +6

Bioorganic & Medicinal Chemistry

BiochemistryG Protein-coupled ReceptorStructure–activity Relationship StudyMedicinePeptide Science +2

Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging

Ayumu Niida, Shigekazu Sasaki, Kazuko Yonemori, +5

Bioorganic & Medicinal Chemistry Letters

Alanine ScansMedicinal ChemistryBiochemistryStructural RequirementsNatural Sciences +8

Application of tri- and tetrasubstituted alkene dipeptide mimetics to conformational studies of cyclic RGD peptides

Shinya Oishi, Kazuhide Miyamoto, Ayumu Niida, +6

Tetrahedron

Cyclic Rgd PeptidesBiochemistryProtein FoldingNatural SciencesConformational Studies +6