Concepedia

Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: A new strategy for generating completely non-fucosylated recombinant therapeutics

Yutaka Kanda, Harue Imai-Nishiya, Reiko Kuni‐Kamochi, Katsuhiro Mori, Miho Inoue, Kazuko Kitajima-Miyama, Akira Okazaki, Shigeru Iida, Kenya Shitara, Mitsuo Satoh

Journal of Biotechnology · 2007 · 123 citations · 26 references

DOI

Concepts

References

26

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

Raphael Clynes, Terri L. Towers, Leonard G. Presta et al. · Nature Medicine · 2000 · 2.7K citations

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Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγRIIIa gene

Guillaume Cartron, Laurent Dacheux, Gilles Salles et al. · Blood · 2002 · 1.9K citations · Full text

, , +16

Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity

Robert L. Shields, Jadine Lai, Rodney G. Keck et al. · Journal of Biological Chemistry · 2002 · 1.8K citations · Full text

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The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

, , +17

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

G Urlaub, Lawrence A. Chasin · Proceedings of the National Academy of Sciences · 1980 · 910 citations

, , +9