Lawrence A. Chasin

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

Michael Wigler, Àngel Pellicer, Saul J. Silverstein et al. · Proceedings of the National Academy of Sciences · 1979 · 1.3K citations · Full text

Aprt+ Phenotype, Protein Expression, Mouse Cells +15

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

G Urlaub, Lawrence A. Chasin · Proceedings of the National Academy of Sciences · 1980 · 908 citations

Reductive Stress, Aldehyde Dehydrogenase, Cellular Enzymology +15

Computational definition of sequence motifs governing constitutive exon splicing

Xiang H.-F. Zhang, Lawrence A. Chasin · Genes & Development · 2004 · 411 citations · Full text

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.

Jack H. Nunberg, Randal J. Kaufman, Robert Schimke et al. · Proceedings of the National Academy of Sciences · 1978 · 394 citations · Full text

Single Chromosome, Cytogenetics, Genetics +19

Nonsense mutations in the dihydrofolate reductase gene affect RNA processing.

Gail Urlaub, Pamela J. Mitchell, Carlos J. Ciudad et al. · Molecular and Cellular Biology · 1989 · 349 citations · Full text

Genome Instability, Dhfr Gene, Natural Sciences +14