Concepedia

Knockout Cell Line Models

Knockout Cell Line Models is a genetic engineering construct in which specific genes are permanently inactivated within a stable, immortalized cell population to enable the systematic study of gene function in a controlled in vitro environment.

141

Publications

8.2K

Citations

1.3K

Authors

405

Institutions

Publications per year

2017–2026

70

Variants

Knockout Cell Lines

Parents

Publications

141

Generating green fluorescent mice by germline transmission of green fluorescent ES cells

Anna‐Katerina Hadjantonakis, Marina Gertsenstein, Masahito Ikawa et al. · Mechanisms of Development · 1998 · 483 citations

, , +16

Production of homozygous mutant ES cells with a single targeting construct.

Richard M. Mortensen, David A. Conner, Stephen Chao et al. · Molecular and Cellular Biology · 1992 · 413 citations · Full text

, , +17

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

Matthew J. Shurtleff, Jun Yao, Yidan Qin et al. · Proceedings of the National Academy of Sciences · 2017 · 352 citations · Full text

, , +17

Inhibitory Effects of B Cells on Antitumor Immunity

Satoshi Inoue, Wolfgang W. Leitner, Basil Golding et al. · Cancer Research · 2006 · 332 citations

, , +17

DNA methylation regulates microRNA expression

Liangfeng Han, P. Dane Witmer, Emily Casey et al. · Cancer Biology & Therapy · 2007 · 328 citations · Full text

, , +16

1–5 of 141

Authors

1.3K

  1. JG
    Jonathan G. Seidman

    Harvard University, United States

    3 publications · 561 citations

    3

    h-index

  2. RM
    Richard M. Mortensen

    University of Michigan, United States

    3 publications · 561 citations

    3

    h-index

  3. SC
    Stephen C. Pak

    University of Pittsburgh, United States

    2 publications · 43 citations

    2

    h-index

  4. IA
    Istvan A Ember

    The University of Texas Medical Branch at Galveston, United States

    2 publications · 28 citations

    2

    h-index

  5. AA
    Anja A. T. Geisterfer-Lowrance

    Brigham and Women's Hospital, United States

    2 publications · 551 citations

    2

    h-index

1–5 of 1.3K

Institutions

405

  1. National Institutes of Health

    Bethesda, United States

    7 h-index

    100 publications

    3K citations

  2. National Cancer Institute

    Bethesda, United States

    7 h-index

    28 publications

    1.6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    18 publications

    539 citations

  4. The University of Osaka

    Osaka, Japan

    6 h-index

    44 publications

    2.3K citations

  5. Brigham and Women's Hospital

    Boston, United States

    5 h-index

    16 publications

    2.6K citations

  6. Baylor College of Medicine

    Houston, United States

    5 h-index

    91 publications

    3.1K citations

  7. Center for Cancer Research

    Bethesda, United States

    5 h-index

    18 publications

    1.1K citations

  8. Université Toulouse III - Paul Sabatier

    Toulouse, France

    4 h-index

    10 publications

    360 citations

1–8 of 405

Venues

  1. PLoS ONE

    5 publications · 155 citations

    5

    h-index

  2. PubMed

    Repository · 4 publications · 160 citations

    4

    h-index

  3. Molecular and Cellular Biology

    MCB · 4 publications · 694 citations

    4

    h-index

  4. Scientific Reports

    3 publications · 116 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 534 citations

    3

    h-index

1–5