Concepedia

Knockout Animal Models

Knockout Animal Model is a type of genetically engineered animal model in which a specific gene is inactivated or "knocked out" to investigate its function by observing the resulting phenotypic alterations.

208

Publications

19.4K

Citations

1.3K

Authors

384

Institutions

Publications per year

2017–2026

62

Variants

Knockout Animal Model

Parents

Children

Publications

208

Effective targeted gene ‘knockdown’ in zebrafish

Aidas Nasevicius, Stephen C. Ekker · Nature Genetics · 2000 · 2.5K citations

, , +10

A conditional knockout resource for the genome-wide study of mouse gene function

William C. Skarnes, Barry P. Rosen, Anthony P. West et al. · Nature · 2011 · 1.8K citations

, , +16

Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain

Joe Z. Tsien, Dong Feng Chen, David J. Gerber et al. · Cell · 1996 · 1.3K citations · Full text

, , +17

The use of animal models in diabetes research

Aileen King · British Journal of Pharmacology · 2012 · 1.3K citations · Full text

, , +17

Animal models in type 2 diabetes research: an overview.

K. K. Srinivasan, Poduri Ramarao · PubMed · 2007 · 724 citations

, , +17

1–5 of 208

Authors

1.3K

  1. WW
    Wolfgang Wurst

    Helmholtz Zentrum München, Germany

    4 publications · 1K citations

    4

    h-index

  2. DA
    David Ayares

    University of Pittsburgh, United States

    4 publications · 186 citations

    4

    h-index

  3. JL
    Jian Lu

    East China Normal University, China

    3 publications · 89 citations

    3

    h-index

  4. DP
    D.R. Powell

    Baylor College of Medicine, United States

    3 publications · 108 citations

    3

    h-index

  5. JR
    John R. Perfect

    Duke Medical Center, United States

    3 publications · 59 citations

    3

    h-index

1–5 of 1.3K

Institutions

384

  1. Chinese Academy of Sciences

    Beijing, China

    7 h-index

    39 publications

    1.5K citations

  2. Wellcome Sanger Institute

    Cambridge, United Kingdom

    7 h-index

    30 publications

    28.7K citations

  3. Harvard University

    Cambridge, United States

    7 h-index

    28 publications

    2.7K citations

  4. Yale University

    New Haven, United States

    5 h-index

    16 publications

    991 citations

  5. National Institutes of Health

    Bethesda, United States

    5 h-index

    20 publications

    2.6K citations

  6. Inserm

    Paris, France

    5 h-index

    23 publications

    2.9K citations

  7. Helmholtz Zentrum München

    Munich, Germany

    5 h-index

    11 publications

    1.3K citations

  8. Mayo Clinic

    Rochester, United States

    5 h-index

    10 publications

    691 citations

1–8 of 384

Venues

  1. PubMed

    Repository · 11 publications · 1.1K citations

    11

    h-index

  2. PLoS ONE

    8 publications · 628 citations

    8

    h-index

  3. Methods in molecular biology

    Book series · 7 publications · 209 citations

    7

    h-index

  4. Nature Genetics

    4 publications · 3.6K citations

    4

    h-index

  5. Nature

    4 publications · 1.9K citations

    4

    h-index

1–5