Concepedia

Knockout Rat Models

Knockout Rat Model is a genetically engineered animal model in which one or more specific genes are inactivated or "knocked out" to study gene function and disease mechanisms in a mammalian system closely related to humans.

264

Publications

11.9K

Citations

1.9K

Authors

584

Institutions

Publications per year

2017–2026

97

Variants

Knockout Rat ModelKnockout Rats

Parents

Publications

264

Molecular cloning and expression analyses of mouse βklotho, which encodes a novel Klotho family protein

Shinji Ito, Satoko Kinoshita, Norihiko Shiraishi et al. · Mechanisms of Development · 2000 · 305 citations

, , +13

Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease

Kuldip D. Dave, Shehan Silva, Niketa P. Sheth et al. · Neurobiology of Disease · 2014 · 227 citations · Full text

, , +17

Production of knockout rats using ENU mutagenesis and a yeast-based screening assay

Jill D. Haag, Kai-Shun Chen, L.A. Shepel et al. · Nature Biotechnology · 2003 · 216 citations

, , +12

Histological, behavioural and neurochemical evaluation of medial forebrain bundle and striatal 6-OHDA lesions as rat models of Parkinson's disease

Hong Yuan, Sophie Sarre, Guy Ebinger et al. · Journal of Neuroscience Methods · 2004 · 211 citations

, , +17

Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis

Bart M. G. Smits, Josine Mudde, José van de Belt et al. · Pharmacogenetics and Genomics · 2006 · 199 citations

, , +17

1–5 of 264

Authors

1.9K

  1. JL
    Jian Lu

    East China Normal University, China

    5 publications · 160 citations

    5

    h-index

  2. EC
    Edwin Cuppen

    University Medical Center Utrecht, Netherlands

    5 publications · 303 citations

    5

    h-index

  3. XW
    Xin Wang

    East China Normal University, China

    5 publications · 160 citations

    5

    h-index

  4. TM
    Tomoji Mashimo

    Kyoto University, Japan

    5 publications · 342 citations

    5

    h-index

  5. AM
    Aron M. Geurts

    Medical College of Wisconsin, United States

    4 publications · 158 citations

    4

    h-index

1–5 of 1.9K

Institutions

584

  1. Inserm

    Paris, France

    12 h-index

    84 publications

    6.8K citations

  2. Medical College of Wisconsin

    Milwaukee, United States

    11 h-index

    45 publications

    1.6K citations

  3. Radboud University Nijmegen

    Nijmegen, The Netherlands

    8 h-index

    25 publications

    1K citations

  4. University of Michigan

    Ann Arbor, United States

    8 h-index

    35 publications

    889 citations

  5. Oregon Health & Science University

    Portland, United States

    7 h-index

    22 publications

    1.5K citations

  6. East China Normal University

    Shanghai, China

    7 h-index

    53 publications

    2.5K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    38 publications

    2.5K citations

  8. Yale University

    New Haven, United States

    7 h-index

    19 publications

    724 citations

1–8 of 584

Venues

  1. PLoS ONE

    7 publications · 362 citations

    7

    h-index

  2. PubMed

    Repository · 6 publications · 222 citations

    6

    h-index

  3. Scientific Reports

    6 publications · 269 citations

    6

    h-index

  4. Human Molecular Genetics

    6 publications · 366 citations

    6

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 6 publications · 313 citations

    6

    h-index

1–5