William C. Skarnes

A conditional knockout resource for the genome-wide study of mouse gene function

William C. Skarnes, Barry P. Rosen, Anthony P. West et al. · Nature · 2011 · 1.8K citations · Full text

Knockout Mouse, Functional Genomics, Genetics +13

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

Tito Serafini, Sophia A. Colamarino, E. David Leonardo et al. · Cell · 1996 · 1.3K citations · Full text

Neuroregeneration, Developmental Biology, Neuroanatomy +9

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

Bin Shen, Jun Zhang, Jiankui Zhou et al. · Nature Methods · 2014 · 832 citations

Crispr-cas9 Nickase, Genetics, Molecular Biology +7

Functional analysis of secreted and transmembrane proteins critical to mouse development

Kevin J. Mitchell, Kathy Pinson, Olivia Kelly et al. · Nature Genetics · 2001 · 399 citations

Protein Secretion, Protein Function, Signal Transduction +11

Defining brain wiring patterns and mechanisms through gene trapping in mice

Philip A. Leighton, Kevin J. Mitchell, Lisa V. Goodrich et al. · Nature · 2001 · 394 citations

Developmental Biology, Neurophysiology, Brain Mechanism +11