Concepedia

Inducible Knockout Models

Inducible Knockout Model is a type of genetically engineered animal model in which the targeted gene disruption is conditionally activated in a temporal and spatially controlled manner through external stimuli, distinguishing it from constitutive knockout models by enabling precise regulation of gene inactivation.

77

Publications

4.6K

Citations

633

Authors

220

Institutions

Publications per year

2017–2026

33

Parents

Publications

77

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Lisa M. Monteggia, Michel Barrot, Craig M. Powell et al. · Proceedings of the National Academy of Sciences · 2004 · 671 citations · Full text

, , +17

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene <i>Hcn4</i>

Mirko Baruscotti, Annalisa Bucchi, Carlo Viscomi et al. · Proceedings of the National Academy of Sciences · 2011 · 267 citations · Full text

, , +14

Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice

Xiao Wang, Fengfeng Li, Liang Xie et al. · Nature Communications · 2018 · 231 citations · Full text

, , +17

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

Sarah J. Tabrizi · Human Molecular Genetics · 2000 · 199 citations

, , +17

Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis

Rie Kajino‐Sakamoto, Maiko Inagaki, Elisabeth Lippert et al. · The Journal of Immunology · 2008 · 145 citations · Full text

, , +17

1–5 of 77

Authors

633

  1. XC
    Xu Cao

    Johns Hopkins University, United States

    2 publications · 251 citations

    2

    h-index

  2. MW
    Mei Wan

    Johns Hopkins University, United States

    2 publications · 251 citations

    2

    h-index

  3. AM
    Alfredo Martı́nez

    National Cancer Institute, United States

    2 publications · 33 citations

    2

    h-index

  4. AB
    Annalisa Bucchi

    University of Milan, Italy

    2 publications · 332 citations

    2

    h-index

  5. SM
    Sonia Martínez-Herrero

    Center for Biomedical Research of La Rioja, Spain

    2 publications · 33 citations

    2

    h-index

1–5 of 633

Institutions

220

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    4 h-index

    18 publications

    6.9K citations

  2. University of Pittsburgh

    Pittsburgh, United States

    3 h-index

    13 publications

    417 citations

  3. Japan Science and Technology Agency

    Tokyo, Japan

    3 h-index

    9 publications

    374 citations

  4. Washington University in St. Louis

    St Louis, United States

    3 h-index

    8 publications

    287 citations

  5. University of Minnesota Medical Center

    Minneapolis, United States

    3 h-index

    14 publications

    665 citations

  6. New York University

    New York, United States

    3 h-index

    8 publications

    875 citations

  7. University of Washington

    Seattle, United States

    3 h-index

    7 publications

    330 citations

  8. University of Michigan

    Ann Arbor, United States

    3 h-index

    11 publications

    405 citations

1–8 of 220

Venues

  1. Nature Communications

    4 publications · 412 citations

    4

    h-index

  2. PLoS ONE

    4 publications · 121 citations

    4

    h-index

  3. Circulation Research

    3 publications · 256 citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 955 citations

    3

    h-index

  5. Frontiers in Physiology

    3 publications · 98 citations

    3

    h-index

1–5