CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

Yoshiya Kawaguchi, Toshihiro Okamoto, Masafumi Taniwaki, +10

Nature Genetics

Cag ExpansionsGenetic DisorderGeneticsPathologyMachado-joseph Disease +7

Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

Yutaka Kanda, Tsuyoshi Yamada, Katsuhiro Mori, +9

Glycobiology

A coding variant in RARG confers susceptibility to anthracycline-induced cardiotoxicity in childhood cancer

Folefac Aminkeng, Amit P. Bhavsar, Henk Visscher, +105

Nature Genetics

Childhood CancerOncogenic AgentMedicineRarg Confers SusceptibilityPathology +5

Nonfucosylated Therapeutic IgG1 Antibody Can Evade the Inhibitory Effect of Serum Immunoglobulin G on Antibody-Dependent Cellular Cytotoxicity through its High Binding to FcγRIIIa

Shigeru Iida, Hirofumi Misaka, Miho Inoue, +7

Clinical Cancer Research

CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin α5β1

Mitsuhiro Hoshijima, Takako Hattori, Miho Inoue, +4

FEBS Letters

Double knockdown of α1,6-fucosyltransferase (FUT8) and GDP-mannose 4,6-dehydratase (GMD) in antibody-producing cells: a new strategy for generating fully non-fucosylated therapeutic antibodies with enhanced ADCC

Harue Imai-Nishiya, Katsuhiro Mori, Miho Inoue, +4

BMC Biotechnology

Establishment of a GDP-mannose 4,6-dehydratase (GMD) knockout host cell line: A new strategy for generating completely non-fucosylated recombinant therapeutics

Yutaka Kanda, Harue Imai-Nishiya, Reiko Kuni‐Kamochi, +7

Journal of Biotechnology

Gdp-mannose 4,6-DehydrataseEngineeringBiochemistryNon-fucosylated Recombinant TherapeuticsGlycobiology +8

Comparison of cell lines for stable production of fucose‐negative antibodies with enhanced ADCC

Yutaka Kanda, Naoko Yamane‐Ohnuki, Naoto Sakai, +11

Biotechnology and Bioengineering

CGRP Induces Differential Regulation of Cytokines from Satellite Glial Cells in Trigeminal Ganglia and Orofacial Nociception

Shaista Afroz, Rieko Arakaki, Takuma Iwasa, +6

International Journal of Molecular Sciences

Cost-Effectiveness Analysis of Recurrence Score-Guided Treatment Using a 21-Gene Assay in Early Breast Cancer

Daphne Tsoi, Miho Inoue, Catherine M. Kelly, +2

The Oncologist