Kazuyasu Nakamura

The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Fucose Depletion from Human IgG1 Oligosaccharide Enhances Binding Enthalpy and Association Rate Between IgG1 and FcγRIIIa

Akira Okazaki, Emi Shoji-Hosaka, Kazuyasu Nakamura et al. · Journal of Molecular Biology · 2004 · 337 citations

Life Sciences, Biochemistry, Immunology +13

Defucosylated Chimeric Anti-CC Chemokine Receptor 4 IgG1 with Enhanced Antibody-Dependent Cellular Cytotoxicity Shows Potent Therapeutic Activity to T-Cell Leukemia and Lymphoma

Rinpei Niwa, Emi Shoji-Hosaka, Mikiko Sakurada et al. · Cancer Research · 2004 · 326 citations

Life Sciences, Immunology, Oncology +13

Enhancement of the Antibody-Dependent Cellular Cytotoxicity of Low-Fucose IgG1 Is Independent of FcγRIIIa Functional Polymorphism

Rinpei Niwa, Shigeki Hatanaka, Emi Shoji-Hosaka et al. · Clinical Cancer Research · 2004 · 228 citations · Full text

Life Sciences, Hematology, Immunology +16

Enhanced Natural Killer Cell Binding and Activation by Low-Fucose IgG1 Antibody Results in Potent Antibody-Dependent Cellular Cytotoxicity Induction at Lower Antigen Density

Rinpei Niwa, Mikiko Sakurada, Yukari Kobayashi et al. · Clinical Cancer Research · 2005 · 189 citations

Life Sciences, Cell Biology, Immunology +16