Concepedia

Publication | Open Access

Enhancement of the Antibody-Dependent Cellular Cytotoxicity of Low-Fucose IgG1 Is Independent of FcγRIIIa Functional Polymorphism

DOIFull Paper Access

228

Citations

31

References

2004

Year

Rinpei Niwa, Shigeki Hatanaka, Emi Shoji-Hosaka, Mikiko Sakurada, Yukari Kobayashi, Aya Uehara, Haruhiko Yokoi, Kazuyasu Nakamura, Kenya Shitara
Clinical Cancer Research

Abstract

The use of low-fucose antibodies might improve the therapeutic effects of anti-CD20 therapy for all patients independent of FcgammaRIIIa phenotype beyond that currently seen with even the most responsive patients.

References

YearCitations

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