Rinpei Niwa

Establishment of <i>FUT8</i> knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity

Naoko Yamane‐Ohnuki, Satoko Kinoshita, Miho Inoue‐Urakubo et al. · Biotechnology and Bioengineering · 2004 · 574 citations

Pharmacy, Biochemistry, Immunology +16

Defucosylated Chimeric Anti-CC Chemokine Receptor 4 IgG1 with Enhanced Antibody-Dependent Cellular Cytotoxicity Shows Potent Therapeutic Activity to T-Cell Leukemia and Lymphoma

Rinpei Niwa, Emi Shoji-Hosaka, Mikiko Sakurada et al. · Cancer Research · 2004 · 326 citations

Life Sciences, Immunology, Oncology +13

IgG subclass-independent improvement of antibody-dependent cellular cytotoxicity by fucose removal from Asn297-linked oligosaccharides

Rinpei Niwa, Akito Natsume, Aya Uehara et al. · Journal of Immunological Methods · 2005 · 242 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Enhancement of the Antibody-Dependent Cellular Cytotoxicity of Low-Fucose IgG1 Is Independent of FcγRIIIa Functional Polymorphism

Rinpei Niwa, Shigeki Hatanaka, Emi Shoji-Hosaka et al. · Clinical Cancer Research · 2004 · 228 citations · Full text

Life Sciences, Hematology, Immunology +16

Enhanced Natural Killer Cell Binding and Activation by Low-Fucose IgG1 Antibody Results in Potent Antibody-Dependent Cellular Cytotoxicity Induction at Lower Antigen Density

Rinpei Niwa, Mikiko Sakurada, Yukari Kobayashi et al. · Clinical Cancer Research · 2005 · 189 citations

Life Sciences, Cell Biology, Immunology +16