Mitsuo Satoh

The Absence of Fucose but Not the Presence of Galactose or Bisecting N-Acetylglucosamine of Human IgG1 Complex-type Oligosaccharides Shows the Critical Role of Enhancing Antibody-dependent Cellular Cytotoxicity

Toyohide Shinkawa, Kazuyasu Nakamura, Naoko Yamane et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

Life Sciences, Biochemistry, Immunology +17

Establishment of <i>FUT8</i> knockout Chinese hamster ovary cells: An ideal host cell line for producing completely defucosylated antibodies with enhanced antibody‐dependent cellular cytotoxicity

Naoko Yamane‐Ohnuki, Satoko Kinoshita, Miho Inoue‐Urakubo et al. · Biotechnology and Bioengineering · 2004 · 574 citations

Pharmacy, Biochemistry, Immunology +16

Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex types

Yutaka Kanda, Tsuyoshi Yamada, Katsuhiro Mori et al. · Glycobiology · 2006 · 375 citations

Pharmacy, Biochemistry, Immunology +17

Structural Comparison of Fucosylated and Nonfucosylated Fc Fragments of Human Immunoglobulin G1

S. Matsumiya, Yoshiki Yamaguchi, Junichi Saito et al. · Journal of Molecular Biology · 2007 · 274 citations

Life Sciences, Biochemistry, Molecular Biology +16

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

Tsunehiro Mizushima, Hirokazu Yagi, Emi Takemoto et al. · Genes to Cells · 2011 · 243 citations · Full text

Life Sciences, Biochemistry, Immunology +17