Concepedia

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Susan Wyllie, Michael G. Thomas, Stephen Patterson, Sabrinia Crouch, Manu De Rycker, Rhiannon Lowe, Stephanie Gresham, Michael D. Urbaniak, Thomas D. Otto, Laste Stojanovski,

Nature · 2018 · 145 citations · 25 references

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25

Leishmaniasis Worldwide and Global Estimates of Its Incidence

Jorge Alvar, Iván Darío Vélez, Caryn Bern et al. · PLoS ONE · 2012 · 5.2K citations · Full text

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Rational design of inhibitors that bind to inactive kinase conformations

Yi Liu, Nathanael S. Gray · Nature Chemical Biology · 2006 · 1.1K citations · Full text

, , +14

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Marcus Bantscheff, Dirk Eberhard, Yann Abraham et al. · Nature Biotechnology · 2007 · 1K citations

, , +14

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Marcus Bantscheff, Carsten Hopf, Mikhail M. Savitski et al. · Nature Biotechnology · 2011 · 666 citations

, , +9

Chromosome and gene copy number variation allow major structural change between species and strains of <i>Leishmania</i>

Matthew B. Rogers, James D. Hilley, Nicholas J. Dickens et al. · Genome Research · 2011 · 460 citations · Full text

, , +15