Sabrinia Crouch

Discovery of a Potent and Specific <i>M. tuberculosis</i> Leucyl-tRNA Synthetase Inhibitor: (<i>S</i>)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[<i>c</i>][1,2]oxaborol-1(3<i>H</i>)-ol (GSK656)

Xianfeng Li, Vincent Hernandez, Fernando Rock et al. · Journal of Medicinal Chemistry · 2017 · 162 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Susan Wyllie, Michael G. Thomas, Stephen Patterson et al. · Nature · 2018 · 145 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +15

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

Rosario Díaz-González, Sandra A. Luengo-Arratta, João Seixas et al. · PLoS neglected tropical diseases · 2014 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Predicting Volume of Distribution in Humans: Performance of In Silico Methods for a Large Set of Structurally Diverse Clinical Compounds

Neha Murad, Kishore Kumar Pasikanti, Benjamin D. Madej et al. · Drug Metabolism and Disposition · 2020 · 56 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Michael G. Thomas, Manu De Rycker, Myriam Ajakane et al. · Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15