Vincent Hernandez

An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site

Fernando Rock, Weimin Mao, A. Yaremchuk et al. · Science · 2007 · 620 citations · Full text

Engineering, Correct Amino Acid, Aminoacyl-trna Synthetase +19

Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis

Stephen J. Baker, Yong-Kang Zhang, Tsutomu Akama et al. · Journal of Medicinal Chemistry · 2006 · 308 citations

5-Fluoro-1,3-dihydro-1-hydroxy-2,1- Benzoxaborole, Medicinal Chemistry, Antifungal Agent +11

Discovery and structure–activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis

Tsutomu Akama, Stephen J. Baker, Yongkang Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 207 citations · Full text

Inflammation, Medicinal Chemistry, Anti-inflammatory +9

Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

Vincent Hernandez, Thibaut Crépin, Andrés Palencia et al. · Antimicrobial Agents and Chemotherapy · 2013 · 195 citations · Full text

Available Antibiotics, Microbial Pathogens, Lead Analogue +24

Discovery of a Potent and Specific <i>M. tuberculosis</i> Leucyl-tRNA Synthetase Inhibitor: (<i>S</i>)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[<i>c</i>][1,2]oxaborol-1(3<i>H</i>)-ol (GSK656)

Xianfeng Li, Vincent Hernandez, Fernando Rock et al. · Journal of Medicinal Chemistry · 2017 · 157 citations · Full text