Manu De Rycker

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Susan Wyllie, Stephen Brand, Michael G. Thomas et al. · Proceedings of the National Academy of Sciences · 2019 · 173 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Comparison of a High-Throughput High-Content Intracellular Leishmania donovani Assay with an Axenic Amastigote Assay

Manu De Rycker, Irene Hallyburton, John Thomas et al. · Antimicrobial Agents and Chemotherapy · 2013 · 149 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +14

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Susan Wyllie, Michael G. Thomas, Stephen Patterson et al. · Nature · 2018 · 145 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +15

Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery

Lorna MacLean, John Thomas, Michael D. Lewis et al. · PLoS neglected tropical diseases · 2018 · 114 citations · Full text

Veterinary Medicine, Microbiology, Pharmacology +15

Tankyrase Polymerization Is Controlled by Its Sterile Alpha Motif and Poly(ADP-Ribose) Polymerase Domains

Manu De Rycker, Carolyn M. Price · Molecular and Cellular Biology · 2004 · 101 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17