Nature Chemical Biology · 2006 · 1.1K citations · 23 references
PharmacyMedicinal ChemistryMolecular BiologyDrug DesignDrug DiscoveryStructural BiologyConformational AnalysisConformational SelectionEnzyme InhibitionLigand BindingMolecular DockingProtein-ligand DockingAllosteric Kinase InhibitorsKinase InhibitorsProtein Kinase InhibitorsRational DesignResidue-directed Inhibitor Design
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Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
Paul Wan, Mathew J. Garnett, S. Mark Roe et al. · Cell · 2004 · 2.8K citations · Full text
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Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
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A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib)
Edgar R. Wood, Anne T. Truesdale, Octerloney B. McDonald et al. · Cancer Research · 2004 · 1.1K citations · Full text
Medicine, Oncology, Pharmacology +14