William Biggs

A small molecule–kinase interaction map for clinical kinase inhibitors

Miles A. Fabian, William Biggs, Daniel K. Treiber et al. · Nature Biotechnology · 2005 · 1.9K citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +12

Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB

Karen Yamamoto, G. González, William Biggs et al. · Nature · 1988 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +15

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

William Biggs, Jill Meisenhelder, Tony Hunter et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +15

Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

Rohit Loomba, Victor Seguritan, Weizhong Li et al. · Cell Metabolism · 2017 · 1.1K citations · Full text

Life Sciences, Microbiology, Molecular Medicine +17

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

Gustavo González, Karen Yamamoto, Wolfgang Fischer et al. · Nature · 1989 · 917 citations

Life Sciences, Cell Biology, Molecular Biology +10