Paul Wan

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

Paul Wan, Mathew J. Garnett, S. Mark Roe et al. · Cell · 2004 · 2.8K citations · Full text

Oncogenic Mutations, Signal Transduction, Signaling Pathway +9

Structures, functions and adaptations of the human LINE-1 ORF2 protein

Eric T. Baldwin, Trevor van Eeuwen, David Hoyos et al. · Nature · 2023 · 107 citations · Full text

Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure

David Komander, Ritu Garg, Paul Wan et al. · The EMBO Journal · 2008 · 66 citations · Full text

Biochemistry, Protein Assembly, Natural Sciences +5

X‐ray Structural Analysis of Tau‐Tubulin Kinase 1 and Its Interactions with Small Molecular Inhibitors

Yafeng Xue, Paul Wan, Per Hillertz et al. · ChemMedChem · 2013 · 37 citations

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific inhibition

Eric T. Baldwin, Matthias Götte, Egor P. Tchesnokov et al. · Proceedings of the National Academy of Sciences · 2022 · 37 citations · Full text

Crystal Structure, Viral Replication, Viral Polymerase Mechanism +18