David Komander

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

Tobias L. Haas, Christoph H. Emmerich, Björn Gerlach et al. · Molecular Cell · 2009 · 753 citations · Full text

Transcriptional Regulation, Tnf-r1 Signaling Complex, Signal Transduction +10

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

Simin Rahighi, Fumiyo Ikeda, Masato Kawasaki et al. · Cell · 2009 · 739 citations · Full text

Protein Function, Signal Transduction, Specific Recognition +9

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink et al. · Cell · 2013 · 614 citations · Full text

Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains

David Komander, Francisca E. Reyes‐Turcu, Julien Licchesi et al. · EMBO Reports · 2009 · 566 citations · Full text

Chemical Biology, Molecular Characterization, Biochemistry +9

Mechanism of phospho-ubiquitin-induced PARKIN activation

Tobias Wauer, Michal Šimíček, Alexander F. Schubert et al. · Nature · 2015 · 486 citations · Full text

Signal Transduction, Signaling Pathway, Autophagy +6