Paul P. Geurink

Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity

Dong Hyuk Shin, Rukmini Mukherjee, Diana Grewe et al. · Nature · 2020 · 1.2K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink et al. · Cell · 2013 · 632 citations · Full text

Life Sciences, Molecular Biology, Oncology +13

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

Theresa Klemm, Gregor Ebert, Dale J. Calleja et al. · The EMBO Journal · 2020 · 494 citations · Full text

Life Sciences, Biochemistry, Infectious Diseases +10

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

Reggy Ekkebus, Sander I. van Kasteren, Yogesh Kulathu et al. · Journal of the American Chemical Society · 2013 · 360 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening

Efrat Resnick, A.R. Bradley, Jinrui Gan et al. · Journal of the American Chemical Society · 2019 · 342 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17