Concepedia

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

Simin Rahighi, Fumiyo Ikeda, Masato Kawasaki, Masato Akutsu, Nobuhiro Suzuki, Ryuichi Kato, Tobias Kensche, Tamami Uejima, Stuart Bloor, David Komander,

Cell · 2009 · 748 citations · 30 references

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30

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

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Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Li Deng, Chen Wang, Erika Spencer et al. · Cell · 2000 · 1.9K citations · Full text

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Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMO

Chee-Kwee Ea, Li Deng, Zong-Ping Xia et al. · Molecular Cell · 2006 · 981 citations · Full text

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Involvement of linear polyubiquitylation of NEMO in NF-κB activation

Fuminori Tokunaga, Shin‐ichi Sakata, Yasushi Saeki et al. · Nature Cell Biology · 2009 · 936 citations

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TAB2 and TAB3 Activate the NF-κB Pathway through Binding to Polyubiquitin Chains

Atsuhiro Kanayama, Rashu B. Seth, Lijun Sun et al. · Molecular Cell · 2004 · 869 citations · Full text

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