Chen Wang

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

Signal Transduction, Signaling Pathway, Cell Regulation +6

The E3 Ubiquitin Ligase AMFR and INSIG1 Bridge the Activation of TBK1 Kinase by Modifying the Adaptor STING

Qiang Wang, Xing Liu, Ye Cui et al. · Immunity · 2014 · 351 citations · Full text

Signal Transduction, Signaling Pathway, Natural Sciences +10

Structural basis for m7G recognition and 2′-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I

Swapnil C. Devarkar, Chen Wang, Matthew T. Miller et al. · Proceedings of the National Academy of Sciences · 2016 · 348 citations · Full text

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon

Chen Wang, Taoyong Chen, Jia Zhang et al. · Nature Immunology · 2009 · 309 citations

Transcriptional Regulation, Cell Regulation, Immunology +8

Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification

He-Xin Shi, Kai S. Yang, Xing Liu et al. · Molecular and Cellular Biology · 2010 · 269 citations · Full text

Immunology, Viral Pathogenesis, Innate Immunity +22