Li Deng

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Chen Wang, Li Deng, Mei Hong et al. · Nature · 2001 · 2.1K citations

Signal Transduction, Signaling Pathway, Cell Regulation +6

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Li Deng, Chen Wang, Erika Spencer et al. · Cell · 2000 · 1.9K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMO

Chee-Kwee Ea, Li Deng, Zong-Ping Xia et al. · Molecular Cell · 2006 · 974 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +9

TAB2 and TAB3 Activate the NF-κB Pathway through Binding to Polyubiquitin Chains

Atsuhiro Kanayama, Rashu B. Seth, Lijun Sun et al. · Molecular Cell · 2004 · 861 citations · Full text

Inflammation, Cytokine, Transcriptional Regulation +14

The TRAF6 Ubiquitin Ligase and TAK1 Kinase Mediate IKK Activation by BCL10 and MALT1 in T Lymphocytes

Lijun Sun, Li Deng, Chee-Kwee Ea et al. · Molecular Cell · 2004 · 686 citations · Full text

Signal Transduction, Autoimmune Disease, Traf6 Ubiquitin Ligase +9