Concepedia

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

Fuminori Tokunaga, Shin‐ichi Sakata, Yasushi Saeki, Yoshinori Satomi, Takayoshi Kirisako, Kiyoko Kamei, Tomoko Nakagawa, Michiko Kato, Shigeo Murata, Shoji Yamaoka,

Nature Cell Biology · 2009 · 936 citations · 25 references

DOI

Concepts

References

25

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Li Deng, Chen Wang, Erika Spencer et al. · Cell · 2000 · 1.9K citations · Full text

, , +16

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

Vincent Chau, John W. Tobias, Andreas Bachmair et al. · Science · 1989 · 1.5K citations

, , +14

Activation of IKK by TNFα Requires Site-Specific Ubiquitination of RIP1 and Polyubiquitin Binding by NEMO

Chee-Kwee Ea, Li Deng, Zong-Ping Xia et al. · Molecular Cell · 2006 · 981 citations · Full text

, , +14

Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity

Zhijian J. Chen, Lana Parent, Tom Maniatis · Cell · 1996 · 959 citations · Full text

, , +10

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB

Thijn R. Brummelkamp, Sebastian Nijman, Annette M.G. Dirac et al. · Nature · 2003 · 956 citations · Full text

, , +12