Yasushi Saeki

Ubiquitin is phosphorylated by PINK1 to activate parkin

Fumika Koyano, Kei Okatsu, Hidetaka Kosako et al. · Nature · 2014 · 1.4K citations

Protein Function, Signal Transduction, Autophagy +4

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

Fuminori Tokunaga, Shin‐ichi Sakata, Yasushi Saeki et al. · Nature Cell Biology · 2009 · 930 citations

Signal Transduction, Signaling Pathway, Cellular Regulatory Mechanism +6

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

Fuminori Tokunaga, Tomoko Nakagawa, Masaki Nakahara et al. · Nature · 2011 · 603 citations

Protein Function, Signal Transduction, Molecular Regulation +7

Mutations in the deubiquitinase gene USP8 cause Cushing's disease

Martín Reincke, Silviu Sbiera, Akira Hayakawa et al. · Nature Genetics · 2014 · 573 citations

Disease Mechanism, Medicine, Genetics +4

The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling

Fumiaki Ohtake, Yasushi Saeki, Satoshi Ishido et al. · Molecular Cell · 2016 · 337 citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +5