Concepedia

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

Paul Wan, Mathew J. Garnett, S. Mark Roe, Sharlene Lee, Dan Niculescu‐Duvaz, Valerie M. Good, Cancer Genome Project, Chris M. Jones, Christopher J. Marshall, Caroline J. Springer,

Cell · 2004 · 2.8K citations · 38 references

DOIFull text

Open access

Concepts

References

38

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Axel T. Brünger, Paul D. Adams, G. Marius Clore et al. · Acta Crystallographica Section D Biological Crystallography · 1998 · 15.8K citations

, , +17

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

, , +16

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

, , +12

Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase

Thomas H. Schindler, William G. Bornmann, Patricia Pellicena et al. · Science · 2000 · 1.8K citations

, , +16

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

Walter Kölch · Biochemical Journal · 2000 · 1.4K citations · Full text

, , +17