S. Mark Roe

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

Paul Wan, Mathew J. Garnett, S. Mark Roe et al. · Cell · 2004 · 2.8K citations · Full text

Medicine, Molecular Biology, Oncology +14

Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

Chrisostomos Prodromou, S. Mark Roe, Ronan O’Brien et al. · Cell · 1997 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

S. Mark Roe, Chrisostomos Prodromou, Ronan O’Brien et al. · Journal of Medicinal Chemistry · 1999 · 999 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex

Maruf M. U. Ali, S. Mark Roe, Cara K. Vaughan et al. · Nature · 2006 · 977 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

Laurent Meijer, Alexios-Leandros Skaltsounis, Prokopios Magiatis et al. · Chemistry & Biology · 2003 · 815 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13