Chrisostomos Prodromou

Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

Chrisostomos Prodromou, S. Mark Roe, Ronan O’Brien et al. · Cell · 1997 · 1.3K citations · Full text

Atp/adp-binding Site, Structural Characterization, Protein Function +11

Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

S. Mark Roe, Chrisostomos Prodromou, Ronan O’Brien et al. · Journal of Medicinal Chemistry · 1999 · 991 citations · Full text

Protein Assembly, Molecular Biology, Antimicrobial Chemotherapy +20

Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex

Maruf M. U. Ali, S. Mark Roe, Cara K. Vaughan et al. · Nature · 2006 · 959 citations · Full text

Crystal Structure, Biochemistry, Protein Folding +7

Activation of the ATPase Activity of Hsp90 by the Stress-Regulated Cochaperone Aha1

Barry Panaretou, Giuliano Siligardi, Philippe Meyer et al. · Molecular Cell · 2002 · 541 citations · Full text

Atpase Activity, Reductive Stress, Signal Transduction +10

Structural and Functional Analysis of the Middle Segment of Hsp90: Implications for ATP Hydrolysis and Client Protein and Cochaperone Interactions

Philippe Meyer, Chrisostomos Prodromou, Bin Hu et al. · Molecular Cell · 2003 · 483 citations · Full text

Protein Chemistry, Protein Function, Biochemistry +12