Concepedia

Author

Matthias Götte

McGill UniversityORCID

Also Known As

Berghuis, Albert, Fuksa, J., Gotte, Matthias, Götte M, Kalyan Das, M Gotte, M Gtte, M Götte, M. Gotte, M. Götte

188

Publications

9.4K

Citations

45

H-Index

78

Concepts

All Affiliations

McGill UniversityUniversity of AlbertaJewish General HospitalGilead Sciences (United States)Emory University
MG

About

Matthias Götte is an author at McGill University specializing in medicine, molecular biology, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

25

40

2.1K

2

Natural Sciences

22

33

2K

3

Biochemistry

17

23

1.5K

4

Engineering

5

5

329

5

Applied Physics

3

3

81

Matthias Götte

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98

Publications

8.5K

Citations

43

H-Index

YearCitations

A living WHO guideline on drugs for covid-19

Arnav Agarwal, Beverley J. Hunt, Miriam Stegemann,

BMJ

2020

1.1K

Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

Calvin J. Gordon, Egor P. Tchesnokov, Emma Woolner,

Journal of Biological Chemistry

2020

1K

The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

Calvin J. Gordon, Egor P. Tchesnokov, Joy Y. Feng,

Journal of Biological Chemistry

2020

878

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

Egor P. Tchesnokov, Joy Y. Feng, Danielle Porter,

Viruses

2019

641

Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template

Calvin J. Gordon, Egor P. Tchesnokov, Raymond F. Schinazi,

Journal of Biological Chemistry

2021

289

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

Laura J. Stevens, Andrea J. Pruijssers, Hery W. Lee,

Science Translational Medicine

2022

236

Nucleic acid polymerases use a general acid for nucleotidyl transfer

Christian Castro, Eric D. Smidansky, Jamie J. Arnold,

Nature Structural & Molecular Biology

2009

219

The M184V Mutation in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Impairs Rescue of Chain-Terminated DNA Synthesis

Matthias Götte, Dominique Arion, Michael A. Parniak,

Journal of Virology

2000

171

Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action

Egor P. Tchesnokov, Calvin J. Gordon, Emma Woolner,

Journal of Biological Chemistry

2020

161

Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases

Christian Castro, Eric D. Smidansky, Kenneth R. Maksimchuk,

Proceedings of the National Academy of Sciences

2007

153

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