Joy Y. Feng

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

Timothy P. Sheahan, Amy Sims, Sarah R. Leist et al. · Nature Communications · 2020 · 1.8K citations · Full text

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

Timothy P. Sheahan, Amy Sims, Rachel L. Graham et al. · Science Translational Medicine · 2017 · 1.6K citations · Full text

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

Small Molecule Gs-5734, Rhesus Monkeys, Medicine +10

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

Maria L. Agostini, Erica L. Andres, Amy Sims et al. · mBio · 2018 · 1.5K citations · Full text

Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

Calvin J. Gordon, Egor P. Tchesnokov, Emma Woolner et al. · Journal of Biological Chemistry · 2020 · 1K citations · Full text