Octerloney B. McDonald

Author

Also Known As

O B McDonald, O. Bradley McDonald, O.B. McDonald, O.B. Mcdonald, O.Bradley McDonald, Octerloney B. McDonald, Octerloney McDonald, Octerloney B. Mcdonald

Publications

2.2K

Citations

H-Index

Concepts

All Affiliations

Research Triangle Park Foundation GlaxoSmithKline (United States)Duke University Hospital Burroughs Wellcome Fund Duke Medical Center

About

Octerloney B. McDonald is an author at Research Triangle Park Foundation specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	16	2K
2	Biochemistry	7	7	385
3	Natural Sciences	6	6	351
4	Engineering	1	1	32
5	Social Sciences	1	1	61

Octerloney B. McDonald

Publications

2.2K

Citations

H-Index

Page 1

	Year	Citations
A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib) Edgar R. Wood, Anne T. Truesdale, Octerloney B. McDonald, Cancer Research Crystal StructureMolecular BiologyCell GrowthTumor BiologyDrug Effect	2004	1.1K
The discovery of potent cRaf1 kinase inhibitors Karen Lackey, Michael Cory, Ronda G. Davis, Bioorganic & Medicinal Chemistry Letters Drug TargetMedicineReceptor Tyrosine KinaseRational Drug DesignPharmacology	2000	205
Discovery of GSK1070916, a Potent and Selective Inhibitor of Aurora B/C Kinase Nicholas D. Adams, Jerry L. Adams, Joelle L. Burgess, Journal of Medicinal Chemistry Aurora B/c KinaseChemoprevention StrategyMolecular BiologyTumor BiologyMolecular Pharmacology	2010	108
Heterogeneity of contractile proteins. A continuum of troponin-tropomyosin expression in mammalian skeletal muscle. Frederick H. Schachat, D Bronson, Octerloney B. McDonald Journal of Biological Chemistry	1985	84
Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors Tara Rheault, Thomas R. Caferro, Scott H. Dickerson, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryMedicinePharmacotherapyAnti-cancer AgentDrug Development	2008	83
Activation of casein kinase II by sphingosine. Octerloney B. McDonald, Yusuf A. Hannun, C. Hugh Reynolds, Journal of Biological Chemistry Molecular PharmacologySignal TransductionMolecular PhysiologyBiochemistrySynthetic Peptide Substrate	1991	69
A Scintillation Proximity Assay for the Raf/MEK/ERK Kinase Cascade: High-Throughput Screening and Identification of Selective Enzyme Inhibitors Octerloney B. McDonald, Wen Ji Chen, Byron Ellis, Analytical Biochemistry Drug TargetHit IdentificationBiochemistryNatural SciencesReceptor Tyrosine Kinase	1999	69
Discovery of Selective Small Molecule Type III Phosphatidylinositol 4-Kinase Alpha (PI4KIIIα) Inhibitors as Anti Hepatitis C (HCV) Agents Anna L. Leivers, Matthew D. Tallant, J. Brad Shotwell, Journal of Medicinal Chemistry Viral ReplicationViral Polymerase StructureHepatitis C VirusMolecular BiologyReplication Organelles	2013	66
Phosphorylation of a Ras-related GTP-binding protein, Rap-1b, by a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase Gr. N Sahyoun, Octerloney B. McDonald, Francis X. Farrell, Proceedings of the National Academy of Sciences NeurotransmissionCam Kinase IiCellular PhysiologySocial SciencesRas-related Gtp-binding Protein	1991	61
Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time1 Kelly Anderson, Zhihong Lai, Octerloney B. McDonald, Biochemical Journal Molecular BiologyAurora BTumor BiologyTumour RegressionMolecular Pharmacology	2009	56

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