Tara Rheault

Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors

Tara Rheault, John Stellwagen, George M. Adjabeng et al. · ACS Medicinal Chemistry Letters · 2013 · 253 citations · Full text

B-raf-driven Tumors, Antitumor Activity, Hyperactive Signaling +16

Dabrafenib; Preclinical Characterization, Increased Efficacy when Combined with Trametinib, while BRAF/MEK Tool Combination Reduced Skin Lesions

Alastair J. King, Marc R. Arnone, Maureen R. Bleam et al. · PLoS ONE · 2013 · 212 citations · Full text

Dermatology, Tumor Biology, Signaling Pathway +17

Ensifentrine, a Novel Phosphodiesterase 3 and 4 Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease: Randomized, Double-Blind, Placebo-controlled, Multicenter Phase III Trials (the ENHANCE Trials)

Antonio Anzueto, Igor Barjaktarević, Thomas M. Siler et al. · American Journal of Respiratory and Critical Care Medicine · 2023 · 119 citations · Full text

Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors

Tara Rheault, Thomas R. Caferro, Scott H. Dickerson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 83 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +5

Enantioselective Conjugate Radical Addition to β‐Acyloxy Acrylate Acceptors: An Approach to Acetate Aldol‐Type Products

Mukund P. Sibi, Jake R. Zimmerman, Tara Rheault · Angewandte Chemie International Edition · 2003 · 57 citations

Conjugate Radical Additions, Engineering, Natural Sciences +13