George M. Adjabeng

Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors

Tara Rheault, John Stellwagen, George M. Adjabeng et al. · ACS Medicinal Chemistry Letters · 2013 · 253 citations · Full text

B-raf-driven Tumors, Antitumor Activity, Hyperactive Signaling +16

Palladium Complexes of 1,3,5,7-Tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane:  Synthesis, Crystal Structure and Use in the Suzuki and Sonogashira Reactions and the α-Arylation of Ketones

George M. Adjabeng, T. Brenstrum, Christopher S. Frampton et al. · The Journal of Organic Chemistry · 2004 · 121 citations

Inorganic Chemistry, Chemical Engineering, Crystal Structure +14

Suzuki cross-coupling reactions of aryl halides in phosphonium salt ionic liquid under mild conditions

James McNulty, Alfredo Capretta, Jeff Dyck et al. · Chemical Communications · 2002 · 107 citations

Aryl Halides, Chemical Engineering, Cross-coupling Reaction +13

Novel Class of Tertiary Phosphine Ligands Based on a Phospha-adamantane Framework and Use in the Suzuki Cross-Coupling Reactions of Aryl Halides under Mild Conditions

George M. Adjabeng, T. Brenstrum, Jeffrey D. Wilson et al. · Organic Letters · 2003 · 93 citations

Cross-coupling Reaction, Engineering, Heterocyclic +15

Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry:  Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β-Hydrogens with Boronic Acids and Alkylboranes

T. Brenstrum, D.A. Gerristma, George M. Adjabeng et al. · The Journal of Organic Chemistry · 2004 · 83 citations

Combinatorial Chemistry, Engineering, Library Synthesis +16