George M. Adjabeng - Concepedia

Author

George M. Adjabeng

Research Triangle Park Foundation

Also Known As

Adjabeng, G., Adjabeng, G.M., George Adjabeng, George M. Adjabeng

Publications

950

Citations

H-Index

Concepts

All Affiliations

Research Triangle Park Foundation GlaxoSmithKline (United States)McMaster University Roche (United States)Array BioPharma (United States)

About

George M. Adjabeng is an author at Research Triangle Park Foundation specializing in chemistry, engineering, and organic chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Engineering	6	6	438
2	Medicine	5	5	406
3	Natural Sciences	3	3	283
4	Biochemistry	3	3	177
5	Biomolecular Engineering	1	1	93

George M. Adjabeng

Publications

930

Citations

H-Index

Page 1

	Year	Citations
Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors Tara Rheault, John Stellwagen, George M. Adjabeng, ACS Medicinal Chemistry Letters B-raf-driven TumorsAntitumor ActivityHyperactive SignalingTumor BiologyMedicinal Chemistry	2013	253
Palladium Complexes of 1,3,5,7-Tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane: Synthesis, Crystal Structure and Use in the Suzuki and Sonogashira Reactions and the α-Arylation of Ketones George M. Adjabeng, T. Brenstrum, Christopher S. Frampton, The Journal of Organic Chemistry Inorganic ChemistryChemical EngineeringCrystal StructureEngineeringVersatile Complex	2004	121
Suzuki cross-coupling reactions of aryl halides in phosphonium salt ionic liquid under mild conditions James McNulty, Alfredo Capretta, Jeff Dyck, Chemical Communications Aryl HalidesChemical EngineeringCross-coupling ReactionAryl ChloridesEngineering	2002	107
Novel Class of Tertiary Phosphine Ligands Based on a Phospha-adamantane Framework and Use in the Suzuki Cross-Coupling Reactions of Aryl Halides under Mild Conditions George M. Adjabeng, T. Brenstrum, Jeffrey D. Wilson, Organic Letters Cross-coupling ReactionEngineeringHeterocyclicTertiary Phosphine LigandsNatural Sciences	2003	93
Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry: Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β-Hydrogens with Boronic Acids and Alkylboranes T. Brenstrum, D.A. Gerristma, George M. Adjabeng, The Journal of Organic Chemistry Combinatorial ChemistryEngineeringLibrary SynthesisOrganic ChemistryChemistry	2004	83
Abstract B88: A selective Raf kinase inhibitor induces cell death and tumor regression of human cancer cell lines encoding B-RafV600E mutation Sylvie Laquerre, Marc R. Arnone, Katherine G. Moss, Molecular Cancer Therapeutics Tumor RegressionB-rafv600e MutationCell DeathSelectivity Towards B-rafCancer Biology	2009	54
Room-Temperature Pd-Catalyzed Amidation of Aryl Bromides Using <i>tert-</i>Butyl Carbamate Swapna Bhagwanth, Alex G. Waterson, George M. Adjabeng, The Journal of Organic Chemistry	2009	46
A mild, one-pot synthesis of disubstituted benzimidazoles from 2-nitroanilines Keith R. Hornberger, George M. Adjabeng, Hamilton D. Dickson, Tetrahedron Letters Organic ChemistryCombinatorial ChemistryDisubstituted BenzimidazolesChemistry	2006	40
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure–activity relationships of benzothiazine-substituted quinolinediones Javier de Vicente, R. Hendricks, David B. Smith, Bioorganic & Medicinal Chemistry Letters Antiviral CompoundViral Polymerase StructureBiochemistryMedicineNon-nucleoside Inhibitors	2009	35
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: Structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides Javier de Vicente, R. Hendricks, David B. Smith, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryAntiviral CompoundBiochemistryMedicineNon-nucleoside Inhibitors	2009	35

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