Concepedia

Cyclin-dependent Kinases

Cyclin-Dependent Kinases is a family of serine/threonine protein kinases that regulate cell cycle progression, cell division, and cell proliferation by requiring association with specific cyclin regulatory subunits for enzymatic activity.

11.4K

Publications

958K

Citations

48.8K

Authors

5.2K

Institutions

Publications per year

2017–2026

1.4K

Variants

Cdks

Parents

Children

Publications

11.4K

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Manuel Serrano, Gregory J. Hannon, David Beach · Nature · 1993 · 3.7K citations

, , +17

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

, , +14

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science · 1994 · 2.8K citations

, , +17

Cyclin is degraded by the ubiquitin pathway

Michael Glotzer, Andrew W. Murray, Marc W. Kirschner · Nature · 1991 · 2.4K citations

, , +6

1–5 of 11.4K

Authors

48.8K

  1. LM
    Laurent Meijer

    Station Biologique de Roscoff, France

    78 publications · 12.5K citations

    54

    h-index

  2. RG
    Richard G. Pestell

    Thomas Jefferson University, United States

    77 publications · 9.9K citations

    52

    h-index

  3. SI
    Steven I. Reed

    Scripps Research Institute, United States

    59 publications · 12.2K citations

    47

    h-index

  4. PS
    Piotr Siciński

    Dana-Farber Cancer Institute, United States

    56 publications · 11.5K citations

    45

    h-index

  5. DB
    David Beach

    Cold Spring Harbor Laboratory, United States

    42 publications · 21.2K citations

    38

    h-index

1–5 of 48.8K

Institutions

5.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    152 h-index

    914 publications

    280.2K citations

  2. Harvard University

    Cambridge, United States

    139 h-index

    1.6K publications

    298.3K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    105 h-index

    1K publications

    182.1K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    98 h-index

    1.3K publications

    142.3K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    83 h-index

    534 publications

    111.2K citations

  6. University of California, San Francisco

    San Francisco, United States

    80 h-index

    426 publications

    90.4K citations

  7. Massachusetts General Hospital

    Boston, United States

    78 h-index

    476 publications

    102K citations

  8. National Institutes of Health

    Bethesda, United States

    77 h-index

    672 publications

    74.2K citations

1–8 of 5.2K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 311 publications · 55.9K citations

    137

    h-index

  2. Journal of Biological Chemistry

    JBC · 739 publications · 66.4K citations

    136

    h-index

  3. Molecular and Cellular Biology

    MCB · 437 publications · 56.9K citations

    133

    h-index

  4. PubMed

    Repository · 776 publications · 66.7K citations

    128

    h-index

  5. The EMBO Journal

    159 publications · 33K citations

    104

    h-index

1–5