Concepedia

Cyclin-dependent Kinase Complexes

Cyclin-Dependent Kinase Complexes is a heterodimeric protein complex consisting of a cyclin-dependent kinase catalytic subunit bound to a regulatory cyclin subunit that activates its kinase activity and directs substrate specificity in a cell cycle-dependent manner.

2.4K

Publications

209.9K

Citations

11.9K

Authors

2.2K

Institutions

Publications per year

2017–2026

314

Variants

Cdk Complexes

Parents

Publications

2.4K

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

p21 is a universal inhibitor of cyclin kinases

Yue Xiong, Gregory J. Hannon, Hui Zhang et al. · Nature · 1993 · 3.4K citations

, , +14

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Kornélia Polyák, Mong-Hong Lee, Hediye Erdjument‐Bromage et al. · Cell · 1994 · 2.1K citations

, , +15

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

Philip D. Jeffrey, Alicia A. Russo, Kornélia Polyák et al. · Nature · 1995 · 1.4K citations

, , +9

New functional activities for the p21 family of CDK inhibitors.

Joshua LaBaer, Michelle D. Garrett, Lauren Stevenson et al. · Genes & Development · 1997 · 1.4K citations · Full text

, , +14

1–5 of 2.4K

Authors

11.9K

  1. LM
    Laurent Meijer

    Station Biologique de Roscoff, France

    20 publications · 2.8K citations

    19

    h-index

  2. YX
    Yue Xiong

    University of North Carolina at Chapel Hill, United States

    19 publications · 6.6K citations

    18

    h-index

  3. HC
    Harish C. Pant

    National Institute of Neurological Disorders and Stroke, United States

    19 publications · 1.6K citations

    17

    h-index

  4. DI
    Dirk Inzé

    Ghent University, Belgium

    13 publications · 2.1K citations

    13

    h-index

  5. AG
    Antonio Giordano

    Temple University, United States

    14 publications · 2.1K citations

    13

    h-index

1–5 of 11.9K

Institutions

2.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    68 h-index

    288 publications

    95.5K citations

  2. Harvard University

    Cambridge, United States

    59 h-index

    312 publications

    37.9K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    49 h-index

    338 publications

    36.5K citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    40 h-index

    196 publications

    54K citations

  5. University of California, San Francisco

    San Francisco, United States

    33 h-index

    113 publications

    18.9K citations

  6. Inserm

    Paris, France

    33 h-index

    194 publications

    17.9K citations

  7. National Institutes of Health

    Bethesda, United States

    32 h-index

    167 publications

    10.9K citations

  8. The University of Texas MD Anderson Cancer Center

    Houston, United States

    29 h-index

    121 publications

    8.8K citations

1–8 of 2.2K

Venues

  1. Molecular and Cellular Biology

    MCB · 139 publications · 18.7K citations

    79

    h-index

  2. Journal of Biological Chemistry

    JBC · 215 publications · 18.4K citations

    76

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 92 publications · 12.2K citations

    64

    h-index

  4. PubMed

    Repository · 133 publications · 9.8K citations

    55

    h-index

  5. Genes & Development

    42 publications · 14.7K citations

    39

    h-index

1–5