Philip D. Jeffrey

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Yunje Cho, Svetlana S. Gorina, Philip D. Jeffrey et al. · Science · 1994 · 2.5K citations

Chromatin, Crystal Structure, Dna Binding +15

Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

Ning Zheng, Brenda A. Schulman, Langzhou Song et al. · Nature · 2002 · 1.5K citations

Structural Biology, Molecular Biology, Protein X-ray Crystallography

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

Philip D. Jeffrey, Alicia A. Russo, Kornélia Polyák et al. · Nature · 1995 · 1.4K citations

Signal Transduction, Signaling Pathway, Molecular Pathway +10

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

Shiqing Li, Karl R. Schmitz, Philip D. Jeffrey et al. · Cancer Cell · 2005 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Immunology +7

Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex

Alicia A. Russo, Philip D. Jeffrey, Andrea K. Patten et al. · Nature · 1996 · 892 citations

Crystal Structure, Cyclin A–cdk2 Complex, Signal Transduction +9