Stephanie Gresham

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Susan Wyllie, Michael G. Thomas, Stephen Patterson et al. · Nature · 2018 · 145 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +15

Candidate Selection and Preclinical Evaluation of <i>N</i> - <i>tert</i> -Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century

Paul M. O’Neill, B. Kevin Park, Alison E. Shone et al. · Journal of Medicinal Chemistry · 2009 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

First-Time-in-Human Study and Prediction of Early Bactericidal Activity for GSK3036656, a Potent Leucyl-tRNA Synthetase Inhibitor for Tuberculosis Treatment

David M. Tenero, Geo Derimanov, Alex Carlton et al. · Antimicrobial Agents and Chemotherapy · 2019 · 73 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for <i>N-tert</i>-Butyl Isoquine

Paul M. O’Neill, Alison E. Shone, Deborah Stanford et al. · Journal of Medicinal Chemistry · 2009 · 61 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Michael G. Thomas, Manu De Rycker, Myriam Ajakane et al. · Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15