Rhiannon Lowe

Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor.

Craig A. Mullen, M M Coale, Rhiannon Lowe et al. · PubMed · 1994 · 223 citations

Medicine, Immunology, Oncology +15

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Susan Wyllie, Michael G. Thomas, Stephen Patterson et al. · Nature · 2018 · 145 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacology +15

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Michael G. Thomas, Manu De Rycker, Myriam Ajakane et al. · Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based <i>Ex Vivo</i> Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice

Nicola Carriglio, Jan Klapwijk, Raisa Jofra Hernández et al. · Human Gene Therapy Clinical Development · 2017 · 13 citations

Medicine, Immunology, Translational Sciences +17