Raisa Jofra Hernández

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Aisha V. Sauer, Immacolata Brigida, Nicola Carriglio et al. · Blood · 2011 · 105 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)–deficient mice and corrects their immune and metabolic defects

Alessandra Mortellaro, Raisa Jofra Hernández, Matteo M. Guerrini et al. · Blood · 2006 · 77 citations · Full text

Pharmacy, Immunology, Molecular Biology +16

Efficacy of Gene Therapy for Wiskott-Aldrich Syndrome Using a WAS Promoter/cDNA-Containing Lentiviral Vector and Nonlethal Irradiation

Francesco Marangoni, Samantha Scaramuzza, Sara Trifari et al. · Human Gene Therapy · 2006 · 77 citations

Medicine, Biotechnology, Immunology +16

Preclinical Safety and Efficacy of Human CD34+ Cells Transduced With Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome

Samantha Scaramuzza, Luca Biasco, Anna Ripamonti et al. · Molecular Therapy · 2012 · 76 citations · Full text

Medicine, Cell Biology, Hematology +15

ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency

Aisha V. Sauer, Emanuela Mrak, Raisa Jofra Hernández et al. · Blood · 2009 · 75 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +15