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Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach

Medicinal ChemistryAldo-keto ReductaseBiochemistryHydroxytriazole DerivativesMedicineNatural SciencesRational Drug DesignPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyDrug Discovery