Agnese Chiara Pippione

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action

Elena Campaner, Alessandra Rustighi, Alessandro Zannini et al. · Nature Communications · 2017 · 142 citations · Full text

Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-<i>a</i>]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors

Stefano Sainas, Agnese Chiara Pippione, Elisa Lupino et al. · Journal of Medicinal Chemistry · 2018 · 68 citations · Full text

Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds

Stefano Sainas, Agnese Chiara Pippione, Marta Giorgis et al. · European Journal of Medicinal Chemistry · 2017 · 60 citations · Full text

X-ray Structural Studies, Medicinal Chemistry, Aldehyde Dehydrogenase +9

Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid

Agnese Chiara Pippione, Irene Maria Carnovale, Davide Bonanni et al. · European Journal of Medicinal Chemistry · 2018 · 49 citations · Full text

Bioisosteric Scaffold, Medicinal Chemistry, Pharmaceutical Science +12

Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3

Marco L. Lolli, Irene Maria Carnovale, Agnese Chiara Pippione et al. · ACS Medicinal Chemistry Letters · 2019 · 49 citations · Full text

Medicinal Chemistry, Biosynthesis, Bioorganic Chemistry +15