Alessandro Giraudo

Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment

Valeria Capurro, Valeria Tomati, Elvira Sondo et al. · International Journal of Molecular Sciences · 2021 · 72 citations · Full text

Medicine, Cell Biology, Molecular Genetics +13

Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies

Agnese Chiara Pippione, Stefano Sainas, Parveen Goyal et al. · European Journal of Medicinal Chemistry · 2018 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach

Agnese Chiara Pippione, Alessandro Giraudo, Davide Bonanni et al. · European Journal of Medicinal Chemistry · 2017 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric γ-aminobutyric acid receptor binding site

Alessandro Giraudo, Jacob Krall, Birgitte Nielsen et al. · European Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Distinctive lipid signatures of bronchial epithelial cells associated with cystic fibrosis drugs, including Trikafta

Nara Liessi, Emanuela Pesce, Clarissa Braccia et al. · JCI Insight · 2020 · 31 citations · Full text

Medicine, Cell Biology, Pharmacology +15