Carol M. Koboldt

Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:  Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

Thomas D. Penning, John J. Talley, Stephen R. Bertenshaw et al. · Journal of Medicinal Chemistry · 1997 · 2K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pharmacological analysis of cyclooxygenase-1 in inflammation

Chris Smith, Yan Zhang, Carol M. Koboldt et al. · Proceedings of the National Academy of Sciences · 1998 · 811 citations

Medicine, Biochemistry, Pharmacology +16

4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib:  A Potent and Selective Inhibitor of COX-2

John J. Talley, David Brown, Jeffery S. Carter et al. · Journal of Medicinal Chemistry · 2000 · 643 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase

James K. Gierse, Scott D. Hauser, David Creely et al. · Biochemical Journal · 1995 · 417 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

A Single Amino Acid Difference between Cyclooxygenase-1 (COX-1) and −2 (COX-2) Reverses the Selectivity of COX-2 Specific Inhibitors

James K. Gierse, Joseph J. McDonald, Scott D. Hauser et al. · Journal of Biological Chemistry · 1996 · 411 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14