Stephen R. Bertenshaw

Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors:  Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1<i>H</i>-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)

Thomas D. Penning, John J. Talley, Stephen R. Bertenshaw et al. · Journal of Medicinal Chemistry · 1997 · 1.9K citations · Full text

<i>N</i>-[[(5-Methyl-3-phenylisoxazol-4-yl)- phenyl]sulfonyl]propanamide, Sodium Salt, Parecoxib Sodium:  A Potent and Selective Inhibitor of COX-2 for Parenteral Administration

John J. Talley, Stephen R. Bertenshaw, David Brown et al. · Journal of Medicinal Chemistry · 2000 · 211 citations · Full text

Pharmaceutical Science, Altmetric Attention Score, Pharmacotherapy +19

Phosphine mediated synthesis of 2-methylidene-3-amino esters and ketones

Stephen R. Bertenshaw, Michaël Kahn · Tetrahedron Letters · 1989 · 63 citations

2-Methylidene-3-amino Esters, Engineering, Organic Chemistry +4

Effect of Phosphoramidon (Endothelin Converting Enzyme Inhibitor) and BQ-123 (Endothelin Receptor Subtype A Antagonist) on Blood Pressure in Hypertensive Rats

Ellen G. McMahon, Maria A. Palomo, Melanie A. Brown et al. · American Journal of Hypertension · 1993 · 46 citations

Lower Map, Hypertension, Cardiovascular Disease +13

Conformationally restricted 1,5-diarylpyrazoles are selective COX-2 inhibitors

Stephen R. Bertenshaw, John J. Talley, D. Joseph Rogier et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 42 citations

Medicinal Chemistry, Medicine, Rational Drug Design +4